Showing posts with label CJD. Show all posts
Showing posts with label CJD. Show all posts

Thursday, November 21, 2013

Case of CJD Disease in New Hampshire

Bill Rutala
by Bill Rutala, Ph.D.
In September 2013, health officials confirmed that a patient who underwent neurosurgery at a New Hampshire hospital earlier in the year had Creutzfeldt-Jacob disease.  The death, and suspicions that the patient may have had the devastating brain ailment, prompted authorities in two states to warn that as many as 13 patients may have been exposed to surgical equipment used during the patient's surgery, thus to the same disease. The now-deceased patient had undergone neurosurgery at a New Hampshire hospital and the patient was later suspected of having sporadic Creutzfeldt-Jakob disease, a rare, rapidly progressing and always-fatal degenerative brain disease. But by the time this diagnosis was suspected, equipment used in the patient's surgery had been used several other operations. This raised the possibility that the equipment might have been contaminated -- especially since normal sterilization procedures are not enough to get rid of the disease proteins, known as prions, tied to Creutzfeldt-Jakob disease -- thus potentially exposing the other patients to infection (Botelho, CNN, September 2013).  This exposure scenario could happen in any hospital and this is why we must remain vigilant and implement practices that minimize its occurrence in our hospitals.
           Creutzfeldt-Jakob disease (CJD) is a degenerative neurologic disorder of humans with an incidence in the United States of approximately 1 case per million population per year. CJD is caused by a proteinaceous infectious agent, or prion.  Prion diseases elicit no immune response, result in a noninflammatory pathologic process confined to the central nervous system, have an incubation period of years, and usually are fatal within 1 year after diagnosis.